Recombinant BRCA1 anticorps (AA 525-575)

N° du produit ABIN7795735

Cet anticorps anti-BRCA1 est un anticorps Lapin Monoclonal détectant BRCA1 dans WB et IP. Adapté pour Souris.

Aperçu rapide pour Recombinant BRCA1 anticorps (AA 525-575) (ABIN7795735)

Antigène: BRCA1 (Breast Cancer 1 (BRCA1))

Type d'anticorp: Recombinant Antibody

Reactivité: Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp BRCA1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: BLR319M

Détail du produit anti-BRCA1 anticorps

Épitope: AA 525-575

Fonction: Rabbit anti-BRCA1 Recombinant Monoclonal Antibody [BLR319M]

Purification: Purified

Immunogène: Between 525 and 575

Isotype: IgG

Information d'application

Indications d'application: IP,6 μL/mg lysate,WB,11000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1000 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2 - 8 °C

Date de péremption: 12 months

Détails sur BRCA1

Antigène: BRCA1 (Breast Cancer 1 (BRCA1))

Autre désignation: BRCA1

Sujet: BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity. BRCA1 functions by regulating the activities of its interacting proteins which mediate processes such as gene transcription, gene repression, protein phosphorylation, and ubiquitination.

ID gène: 12189

UniProt: P48754

Pathways: Cycle Cellulaire, Réparation de l'ADN, Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Response to DNA Damage Stimulus